Ruben Ramirez discusses self-absolution, defining it as the act of freeing oneself from guilt or blame without external validation. He emphasizes the importance of acknowledging one's mistakes and learning from them without justification. Ramirez shares his personal journey of overcoming failures and finding happiness through internal self-awareness and acceptance. He highlights the significance of having a supportive partner and the need to look within for true self-understanding. Ramirez encourages listeners to embrace their authentic selves, live for their own happiness, and grow through self-acceptance and contentment.