Clearer Thinking is a podcast about ideas that truly matter. If you enjoy learning about powerful, practical concepts and frameworks, wish you had more deep, intellectual conversations in your life, or are looking for non-BS self-improvement, then we think you'll love this podcast! Each week we invite a brilliant guest to bring four important ideas to discuss for an in-depth conversation. Topics include psychology, society, behavior change, philosophy, science, artificial intelligence, math, economics, self-help, mental health, and technology. We focus on ideas that can be applied right now to make your life better or to help you better understand yourself and the world, aiming to teach you the best mental tools to enhance your learning, self-improvement efforts, and decision-making. • We take on important, thorny questions like: • What's the best way to help a friend or loved one going through a difficult time? How can we make our worldviews more accurate? How can we hone the accuracy of our thinking? What are the advantages of using our "gut" to make decisions? And when should we expect careful, analytical reflection to be more effective? Why do societies sometimes collapse? And what can we do to reduce the chance that ours collapses? Why is the world today so much worse than it could be? And what can we do to make it better? What are the good and bad parts of tradition? And are there more meaningful and ethical ways of carrying out important rituals, such as honoring the dead? How can we move beyond zero-sum, adversarial negotiations and create more positive-sum interactions?
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Clearer Thinking is a podcast about ideas that truly matter. If you enjoy learning about powerful, practical concepts and frameworks, wish you had more deep, intellectual conversations in your life, or are looking for non-BS self-improvement, then we think you'll love this podcast! Each week we invite a brilliant guest to bring four important ideas to discuss for an in-depth conversation. Topics include psychology, society, behavior change, philosophy, science, artificial intelligence, math, economics, self-help, mental health, and technology. We focus on ideas that can be applied right now to make your life better or to help you better understand yourself and the world, aiming to teach you the best mental tools to enhance your learning, self-improvement efforts, and decision-making. • We take on important, thorny questions like: • What's the best way to help a friend or loved one going through a difficult time? How can we make our worldviews more accurate? How can we hone the accuracy of our thinking? What are the advantages of using our "gut" to make decisions? And when should we expect careful, analytical reflection to be more effective? Why do societies sometimes collapse? And what can we do to reduce the chance that ours collapses? Why is the world today so much worse than it could be? And what can we do to make it better? What are the good and bad parts of tradition? And are there more meaningful and ethical ways of carrying out important rituals, such as honoring the dead? How can we move beyond zero-sum, adversarial negotiations and create more positive-sum interactions?
Evidence-Based Medicine and its discontents (with Gordon Guyatt)
Clearer Thinking with Spencer Greenberg
1 hour 15 minutes 12 seconds
1 week ago
Evidence-Based Medicine and its discontents (with Gordon Guyatt)
Read the full transcript here. (https://podcast.clearerthinking.org/episode/252/#transcript) • How were decisions made about which treatments to trust before the advent of "evidence-based" medicine? How strong are biological arguments for or against various treatments? When did the Evidence-Based Medicine (EBM) movement begin? How did the EBM movement overcome initial resistance among medical professionals? What resources do doctors have at their disposals to find up-to-date information about treatment efficacies? Why is the pharmaceutical industry allowed such influence over information about treatments? What is the GRADE approach to EBM? What does EBM have to say about the role of patient preferences and values? How bad is being overweight? What are "surrogate" or "substitute" outcomes? How rigorous is the Diagnostic and Statistical Manual of Mental Disorders (DSM)? How often do treatments suffer from a lack of high-quality evidence of an effect versus plenty of high-quality evidence of a lack of an effect? What's the state of evidence about the placebo effect? What are the most exciting current initiatives in EBM? • Gordon Guyatt is a McMaster University Distinguished Professor. His work has focused on Evidence-Based Medicine and promoting high-quality healthcare without financial barriers for all Canadians. His Order of Canada citation acknowledges both contributions. He has been honored as a Canadian Institute of Health Research Researcher of the Year and a member of the Canadian Medical Hall of Fame. Learn more about Gordon and his work at clarityresearch.ca (https://www.clarityresearch.ca/). • Further reading • "This is why you shouldn’t believe that exciting new medical study" by Julia Belluz @ Vox (https://www.vox.com/2015/3/23/8264355/research-study-hype) • Staff • Spencer Greenberg (https://www.spencergreenberg.com/) — Host / Director • Josh Castle (mailto:joshrcastle@gmail.com) — Producer • Ryan Kessler (https://tone.support/) — Audio Engineer • Uri Bram (https://uribram.com/) — Factotum • WeAmplify (https://www.weamplify.info/) — Transcriptionists • Music • Broke for Free (https://freemusicarchive.org/music/Broke_For_Free/Something_EP/Broke_For_Free_-_Something_EP_-_05_Something_Elated) • Josh Woodward (https://www.joshwoodward.com/song/AlreadyThere) • Lee Rosevere (https://archive.org/details/MusicForPodcasts04/Lee+Rosevere+-+Music+for+Podcasts+4+-+11+Keeping+Stuff+Together.flac) • Quiet Music for Tiny Robots (https://www.freemusicarchive.org/music/Quiet_Music_for_Tiny_Robots/The_February_Album/05_Tiny_Robot_Armies) • wowamusic (https://gamesounds.xyz/?dir=wowamusic) • zapsplat.com (https://www.zapsplat.com/music/summer-haze-slow-chill-out-house-track-with-a-modern-pop-feel-warm-piano-chords-underpin-the-track-with-warm-pads-and-a-repetitive-synth-arpeggio/) • Affiliates • Clearer Thinking (https://www.clearerthinking.org/) • GuidedTrack (https://guidedtrack.com/) • Mind Ease (https://mindease.io/) • Positly (https://positly.com/) • UpLift (https://www.uplift.app/) [Read more: https://podcast.clearerthinking.org/episode/252/gordon-guyatt-evidence-based-medicine-and-its-discontents]
Clearer Thinking with Spencer Greenberg
Clearer Thinking is a podcast about ideas that truly matter. If you enjoy learning about powerful, practical concepts and frameworks, wish you had more deep, intellectual conversations in your life, or are looking for non-BS self-improvement, then we think you'll love this podcast! Each week we invite a brilliant guest to bring four important ideas to discuss for an in-depth conversation. Topics include psychology, society, behavior change, philosophy, science, artificial intelligence, math, economics, self-help, mental health, and technology. We focus on ideas that can be applied right now to make your life better or to help you better understand yourself and the world, aiming to teach you the best mental tools to enhance your learning, self-improvement efforts, and decision-making. • We take on important, thorny questions like: • What's the best way to help a friend or loved one going through a difficult time? How can we make our worldviews more accurate? How can we hone the accuracy of our thinking? What are the advantages of using our "gut" to make decisions? And when should we expect careful, analytical reflection to be more effective? Why do societies sometimes collapse? And what can we do to reduce the chance that ours collapses? Why is the world today so much worse than it could be? And what can we do to make it better? What are the good and bad parts of tradition? And are there more meaningful and ethical ways of carrying out important rituals, such as honoring the dead? How can we move beyond zero-sum, adversarial negotiations and create more positive-sum interactions?
