The Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (CGA-IGC) was established in 1995 to improve understanding of the basic science of inherited colorectal cancer and the clinical management of affected families, with an emphasis on the particular aspects of caring for families living in the Americas. The Expert Approach to Hereditary Gastrointestinal Cancers podcast series (seasons 1 and 2), and more recently, the Journal Club podcast series (season 3, 4, 5), are presented by the CGA-IGC Education Committee.
All content for CGA-IGC Podcast Series is the property of CGA-IGC and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
The Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (CGA-IGC) was established in 1995 to improve understanding of the basic science of inherited colorectal cancer and the clinical management of affected families, with an emphasis on the particular aspects of caring for families living in the Americas. The Expert Approach to Hereditary Gastrointestinal Cancers podcast series (seasons 1 and 2), and more recently, the Journal Club podcast series (season 3, 4, 5), are presented by the CGA-IGC Education Committee.
Episode 8: S.5 Ep.8 PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer
CGA-IGC Podcast Series
21 minutes
2 years ago
Episode 8: S.5 Ep.8 PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer
This episode is hosted by Matt Yurgelun, M.D, a GI medical oncologist at the Dana-Farber Cancer Institute in Boston, MA, and features a discussion between Zsofia Stadler, M.D, a GI medical oncologist at the Memorial Sloan Kettering Cancer Center, New York, NY and Andrea Cercek, M.D, a GI medical oncologist also at the Memorial Sloan Kettering Cancer Center, New York, NY.Together they discuss "PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer" which was published in the New England Journal of Medicine and found here https://pubmed.ncbi.nlm.nih.gov/35660797/This study showed a remarkable response to immune checkpoint inhibitors in Lynch syndrome-associated rectal cancers. This exciting work is reviewed and includes insightful discussion of the design, outcomes, side effects, and future questions raised by researchers.This episode was recorded on October 25th, 2022 and reflects expert opinion at the time of the recording. If you enjoyed this podcast, you can listen to more high quality scientific podcasts here
CGA-IGC Podcast Series
The Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (CGA-IGC) was established in 1995 to improve understanding of the basic science of inherited colorectal cancer and the clinical management of affected families, with an emphasis on the particular aspects of caring for families living in the Americas. The Expert Approach to Hereditary Gastrointestinal Cancers podcast series (seasons 1 and 2), and more recently, the Journal Club podcast series (season 3, 4, 5), are presented by the CGA-IGC Education Committee.
