Welcome to Cardiology Today – Recorded November 05, 2025. This episode summarizes 5 key cardiology studies on topics like computed tomography emphysema and population structure. Key takeaway: Aortic Stenosis: Leaflet-Specific Pathology Revealed. Article Links: Article 1: Impact of standardized team-based care on cardiogenic shock outcomes over time. (ESC heart failure) Article 2: SPIROMICS HF: Rationale, Design, and Reproducibility of Measures. (Circulation. Heart failure) Article 3: Clinical and Cardiovascular Magnetic Resonance Characteristics of Veteran Male Endurance Athletes With Atrial Fibrillation: VENTOUX-AF. (Journal of the American Heart Association) Article 4: Dual Contrast-Enhanced Microcomputed Tomography Uncovers Leaflet-Dependent Patterns of Macrocalcification, Fibrous Extracellular Matrix Remodeling, and Adipocyte Degeneration in Calcific Aortic Stenosis. (Journal of the American Heart Association) Article 5: Admixture Mapping of Lipid Traits in Hispanic Americans. (Journal of the American Heart Association) Full episode page: https://podcast.explainheart.com/podcast/aortic-stenosis-leaflet-specific-pathology-revealed-11-05-25/ Featured Articles Article 1: Impact of standardized team-based care on cardiogenic shock outcomes over time. Journal: ESC heart failure PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41189091 Summary: This study investigated the impact of implementing standardized team-based protocols on cardiogenic shock outcomes over time. Researchers analyzed 1453 consecutive patients from a single-center cardiogenic shock registry, comparing outcomes between two periods: 2017-2019 and 2020-2022. This methodology aimed to determine the influence of multidisciplinary management strategies on patient outcomes. The research establishes a crucial framework for evaluating the effectiveness of structured care approaches in this critical condition. Article 2: SPIROMICS HF: Rationale, Design, and Reproducibility of Measures. Journal: Circulation. Heart failure PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41190426 Summary: HeF.pEF: Rationale, Design, and Reproducibility of Measures. The S.P.I.R.O.M.I.C.S. HeF.pEF study outlines its rationale and design for investigating the complex interplay between chronic obstructive pulmonary disease and Heart Failure with Preserved Ejection Fraction. This research specifically tests hypotheses linking new computed tomography emphysema subtypes with distinct cardiovascular phenotypes, including cor pulmonale and cor pulmonale parvus. The study also focuses on common airway branch variations and the reproducibility of its measures, establishing a robust framework for future discoveries. This work is crucial for identifying shared underlying mechanisms and improving management strategies for patients with these often coexisting conditions. Article 3: Clinical and Cardiovascular Magnetic Resonance Characteristics of Veteran Male Endurance Athletes With Atrial Fibrillation: VENTOUX-AF. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41182011 Summary: The V.E.N.T.O.U.X.-A.F. cross-sectional study investigated factors associated with atrial fibrillation in 39 veteran male endurance athletes, a population known for increased A.fib risk. Researchers aimed to determine if left atrial remodeling, assessed by cardiovascular magnetic resonance, exercise blood pressure, and bradyarrhythmia detected by implantable loop recorders, were linked to atrial fibrillation. This research provides a crucial methodological approach to unravel the unclear pathogenesis of atrial fibrillation in this unique athletic cohort. The findings will help inform targeted screening and preventive strategies for these individuals. Article 4: Dual Contrast-Enhanced Microcomputed Tomography Uncovers Leaflet-Dependent Patterns of Macrocalcification, Fibrous Extracellular Matrix Remodeling, and Adipocyte Degeneration in Calcific Aortic Stenosis. Journal: Journal of the