Lung metastases affect 20-54% of patients with extrathoracic cancers, dramatically reducing survival rates – breast cancer survival drops from 96% to 21% with lung spread, while colorectal cancer survival falls from 91% to below 10% with metastasis. These secondary tumors, most commonly originating from breast, colorectal, and prostate tumors, present diagnostic challenges due to non-specific or absent symptoms until advanced stages. Despite these obstacles, innovative treatment approaches like TACE and dendritic cell therapy now offer patients new hope, effectively targeting malignant cells while preserving lung function and significantly improving both quality of life and prognosis.

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