There is a huge gap between organ need and organ availability for transplants due to long waitlists and organ shortages. In response, scientists have been researching how animal organ donation, or Xenotransplantation, can help close this gap. With new advances in synthetic biology, xenotransplantation is becoming a real alternative. But how does it work? Is it safe? Is it ethical? Join the Pittsburgh iGEM team as they discuss animal organ donation and the current ethical issues it faces.