In this episode, our hosts sit down with Dr. Jonathan Cammack, Extension Livestock Entomologist at Oklahoma State University, to discuss the troubling northward advance of the New World Screwworm. Once eradicated from the U.S. in the late 20th century, this destructive pest is again making headlines as it moves from Central America into Mexico—now only about 300 miles from the U.S. border. Dr. Cammack explains the history of eradication efforts, including the groundbreaking sterile fly release program, and details why current prevention depends on vigilant monitoring, quick wound treatment, and international cooperation. The discussion also covers the severe impact that screwworm infestations have on both livestock and wildlife, drawing parallels to the devastating losses seen in Florida’s endangered Key Deer population. From treatment options and insecticide limitations to the importance of adjusting calving seasons, this episode offers a deep dive into strategies producers and wildlife managers can take to stay ahead of the threat. Plus, listeners get an update on another invasive pest: the recently detected Asian Longhorned Tick in northeast Oklahoma.