Approaches to Alzheimer's

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BioTech Breakdown

BioTechPassion

24 episodes

5 days ago

If you're keen on exploring biotechnology and understanding various ideas that propel us to the future, you're at the right place. My name is Raghav and I created this podcast because I couldn't find anyplace where I could clearly learn the mechanisms behind biotech innovations in simple terms. So I decided to take it upon myself to provide this joyous service to others who are as passionate for biotechnology as me!

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Approaches to Alzheimer's

BioTech Breakdown

5 minutes 15 seconds

1 year ago

Approaches to Alzheimer's

Join me as we dive into the mechanism behind Alzheimer's disease and different approaches in development to treat this condition!

Sources:

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2) E;, Wegmann S;Biernat J;Mandelkow. “A Current View on Tau Protein Phosphorylation in Alzheimer’s Disease.” Current Opinion in Neurobiology, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/33892381/#:~:text=Elevated%20phosphorylation%20and%20aggregation%20of,modifications%20in%20the%20disease%20context. Accessed 13 Apr. 2024.

3) Schubert, Charlotte. “Family of protein fragments promises fresh view of alzheimer’s disease.” Proceedings of the National Academy of Sciences, vol. 116, no. 23, 4 June 2019, pp. 11082–11084, https://doi.org/10.1073/pnas.1905886116.

4) Zheng, Hui, and Edward H Koo. “The Amyloid Precursor Protein: Beyond Amyloid - Molecular Neurodegeneration.” BioMed Central, BioMed Central, 3 July 2006, molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-1-5.

5) Person. “What Is Anti-Amyloid Therapy for Alzheimer’s Disease?” Nebraska Medicine Omaha, NE, Nebraska Medicine, 1 June 2023, www.nebraskamed.com/health/conditions-and-services/what-is-anti-amyloid-therapy-for-alzheimers-disease.

6) “Anti-Amyloid Therapies for Alzheimer’s Disease.” WebMD, WebMD, www.webmd.com/alzheimers/anti-amyloid-therapies-alzheimers. Accessed 13 Apr. 2024.

7) Menting, Kelly Willemijn, and Jurgen A H R Claassen. “Β-Secretase Inhibitor; a Promising Novel Therapeutic Drug in Alzheimer’s Disease.” Frontiers in Aging Neuroscience, U.S. National Library of Medicine, 21 July 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4104928/.

8) Mullard, Asher. “BACE Failures Lower Ad Expectations, Again.” Nature News, Nature Publishing Group, 30 May 2018, www.nature.com/articles/nrd.2018.94.

9) M, Arbel, et al. “Give BACE Inhibitors a Second Chance?” ALZFORUM, www.alzforum.org/news/conference-coverage/give-bace-inhibitors-second-chance. Accessed 13 Apr. 2024.