This episode highlights a promising advancement in Alzheimer’s disease treatment using donepezil-loaded nanoparticles. We explore how nanotechnology enhances the delivery and efficacy of donepezil—an acetylcholinesterase inhibitor commonly prescribed for Alzheimer’s—by improving brain targeting, reducing side effects, and crossing the blood-brain barrier more efficiently. The discussion dives into the science of drug-loaded nanoparticles, their formulation strategies, and their potential to revolutionize neurodegenerative disease therapy. Ideal for listeners interested in pharmaceutical innovation, neurology, and nanomedicine.