Feedback 00:52 Intro 02:00 What is Haemophilia A? 03:00 Factor VIII, Pathogenesis of Haemophilia A 07:10 Structure of Factor VIII (exam pearl) 300kDHeavy (A1 A2, B) + Light Chain (A3, C1, C2) bound by a metal ions *Calcium*A subunits are 30% homologousB subunit (variable region) is cleaved by thrombin to get Factor VIIIaC1 and C2 help bind to VWFGood to r/o VWF10:55 Epidemiology and history taking- X-linked recessive Factor VIII is (mostly) feminist.....Turners syndrome, Androgen Insensitivit...
All content for Basics to Brilliance: Haematology Podcast is the property of Basics To Brilliance and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Feedback 00:52 Intro 02:00 What is Haemophilia A? 03:00 Factor VIII, Pathogenesis of Haemophilia A 07:10 Structure of Factor VIII (exam pearl) 300kDHeavy (A1 A2, B) + Light Chain (A3, C1, C2) bound by a metal ions *Calcium*A subunits are 30% homologousB subunit (variable region) is cleaved by thrombin to get Factor VIIIaC1 and C2 help bind to VWFGood to r/o VWF10:55 Epidemiology and history taking- X-linked recessive Factor VIII is (mostly) feminist.....Turners syndrome, Androgen Insensitivit...
Feedback 00:00 Intro 04:25 Automated Methods of Measuring a Clot 05:50 Scenario 1 & Pre-Analytical Variables 11:50 HIL Index & Patient Factors 15:55 Blood Tube Basics 21:10 Nitty Gritties- What Happens When We Send a PT? 23:20 PT vs INR for Warfarin- Going Down The Rabbit Hole... 26:35 Heparin Neutralising Buffer 29:00 APTT 33:05 Summary (& an honorable mention)
Basics to Brilliance: Haematology Podcast
Feedback 00:52 Intro 02:00 What is Haemophilia A? 03:00 Factor VIII, Pathogenesis of Haemophilia A 07:10 Structure of Factor VIII (exam pearl) 300kDHeavy (A1 A2, B) + Light Chain (A3, C1, C2) bound by a metal ions *Calcium*A subunits are 30% homologousB subunit (variable region) is cleaved by thrombin to get Factor VIIIaC1 and C2 help bind to VWFGood to r/o VWF10:55 Epidemiology and history taking- X-linked recessive Factor VIII is (mostly) feminist.....Turners syndrome, Androgen Insensitivit...
