Arkana Advances is a research podcast, hosted by Dr. Rebecca May, discussing the work of Arkana physicians and scientists as they ask questions that lead to advancing the understanding of disease.
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Arkana Advances is a research podcast, hosted by Dr. Rebecca May, discussing the work of Arkana physicians and scientists as they ask questions that lead to advancing the understanding of disease.
Resistant Starch Slows the Progression of CKD in the 5/6 Nephrectomy Mouse Model
Arkana Advances
11 minutes 21 seconds
3 years ago
Resistant Starch Slows the Progression of CKD in the 5/6 Nephrectomy Mouse Model
In patients with chronic kidney disease, toxins normally excreted by the kidney continue to circulate, leading to increased kidney damage. The gut microbiome likely plays a role in this damage and contributes to systemic inflammation. Supplementation with dietary fiber (resistant starch) may prevent this kidney damage. This study uses a mouse model of chronic kidney disease and showed that mice fed resistant starch had significantly less kidney fibrosis. A diet including resistant starch altered the gut microbiome, with changes detected in proteins involved in gut permeability and the inflammatory response. This dietary change may improve outcomes in patients living with chronic kidney disease.
Read the paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547583/pdf/PHY2-8-e14610.pdf
[embed]https://youtu.be/QGY_mcILcIQ[/embed]
Arkana Advances
Arkana Advances is a research podcast, hosted by Dr. Rebecca May, discussing the work of Arkana physicians and scientists as they ask questions that lead to advancing the understanding of disease.
