In this episode of the American Brachytherapy Society podcast, Dr. Alexandra Stewart, Consultant Clinical Oncologist at the Royal Surrey, discusses the evolving role of rectal brachytherapy in non-operative management of rectal cancer. Drawing from her expertise and international experience, Dr. Stewart explores key findings from the OPERA trial, patient selection criteria, dosing strategies, and the latest advancements in contact X-ray brachytherapy (CXB) techniques. She also highlights the impact of treatment protocols on clinical outcomes and future directions, including insights into the TRESOR trial. Tune in for an in-depth conversation on how brachytherapy is shaping the future of rectal cancer care.