Adverse Reactions

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Adverse Reactions

Anne Chappelle, PhD, and David Faulkner, PhD

32 episodes

9 months ago

From studying polluted waters off the coast of California to explaining the feasibility of a fungal-based zombie outbreak at San Diego Comic Con, Kari Sant, PhD, Michigan State University, discusses her passion projects with co-hosts Anne Chappelle, PhD, DABT, and David Faulkner, PhD, DABT. Dr. Sant also reveals what it is like to start a new lab when you change institutions.About the GuestKari Sant, PhD, is an Associate Professor of pharmacology and toxicology in the College of Veterinary Me...

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All content for Adverse Reactions is the property of Anne Chappelle, PhD, and David Faulkner, PhD and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

From studying polluted waters off the coast of California to explaining the feasibility of a fungal-based zombie outbreak at San Diego Comic Con, Kari Sant, PhD, Michigan State University, discusses her passion projects with co-hosts Anne Chappelle, PhD, DABT, and David Faulkner, PhD, DABT. Dr. Sant also reveals what it is like to start a new lab when you change institutions.About the GuestKari Sant, PhD, is an Associate Professor of pharmacology and toxicology in the College of Veterinary Me...

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Episodes (20/32)

Adverse Reactions

Testing the Waters

From studying polluted waters off the coast of California to explaining the feasibility of a fungal-based zombie outbreak at San Diego Comic Con, Kari Sant, PhD, Michigan State University, discusses her passion projects with co-hosts Anne Chappelle, PhD, DABT, and David Faulkner, PhD, DABT. Dr. Sant also reveals what it is like to start a new lab when you change institutions.About the GuestKari Sant, PhD, is an Associate Professor of pharmacology and toxicology in the College of Veterinary Me...

10 months ago

26 minutes

Adverse Reactions

Boom! When Evolutionary Biology and Toxicology Collide

Noah Whiteman, PhD, a professor at UC Berkeley, shares his unique perspective on toxins, stemming from his background in entomology and plant-insect interactions. He explores how toxins impact the ecology and evolution of various organisms, from insects to humans, with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.About the GuestNoah Whiteman, PhD, is Professor of Genetics, Genomics, Evolution, and Development in the Department of Molecular & Cell Biology and the Department of Int...

10 months ago

28 minutes

Adverse Reactions

Cardiovascular Risks from Low-Level Metal Mixtures

Sometimes negative results can be just as interesting as positive ones. Nivetha Subramaniam, a student at McGill University, discusses her research regarding the potential cardiovascular risks from exposure to mixtures of arsenic and cadmium with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.About the GuestNivetha Kamalavannan Subramaniam is a PhD student at McGill University in Canada. She is the recipient of the McGill Dr. Morris Karmazyn and Dr. Margaret P. Moffat Fellowship in Car...

10 months ago

27 minutes

Adverse Reactions

Tox in Your Backyard

From Superfund remediation sites near neighborhoods to wartime combat zones, toxicology is everywhere, which is why many states employ toxicologists on their public health teams. Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, speak with Julie Miller, PhD, Public Health Toxicologist for the Commonwealth of Pennsylvania, about the impacts of stress and environmental exposures on public health.About the GuestJulie Miller, PhD, Public Health Toxicologist, Pennsylvania Department of Public...

10 months ago

27 minutes

Adverse Reactions

Toxicology Is a Team Sport: The Science of Working Together

Did you know that there are scientists who study teamwork? Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, DABT, speak with Stephen Fiore, PhD, Director, Cognitive Sciences Laboratory, about the art and science of working in teams and what you can do to improve teamwork in your lab, department, etc.About the GuestStephen M. Fiore, PhD, is Director, Cognitive Sciences Laboratory, and Professor with the University of Central Florida's Cognitive Sciences Program in the Department of Philo...

11 months ago

26 minutes

Adverse Reactions

Pipping the Scales with Zebrafish

Fish on treadmills? Lisa Truong, PhD, MBA, Oregon State University, discusses the unique ways that they test exposure effects using zebrafish. Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, also ask her about the benefits of having an MBA as a scientist.About the GuestThe overall goal of Lisa Truong's research program is to utilize the zebrafish model to help build computational predictive toxicity models. Secondarily, she aims to move the field to be less reliant on animal testing an...

11 months ago

25 minutes

Adverse Reactions

Snow Big Deal? Similar Exposures, Different Outcomes

Can two people experience the same exposure and have different reactions to both chemical and non-chemical stressors? Yes, according to Samantha "Sam" Snow and a team of toxicologists, epidemiologists, exposure scientists, and others who assess risk. Dr. Snow talks with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, about exposure science, new approach methodologies, and forming the SOT Out Toxicologists and Allies Special Interest Group.About the GuestSamantha Snow, PhD, DABT, is a D...

11 months ago

27 minutes

Adverse Reactions

High Intensity Sweeteners with a Sugar Czar

Whether its found in nature or composed by chemists a sweetener undergoes the same evaluations, according to Corey Scott, PhD, Principal Nutritionist, Cargill. Dr. Scott explains to co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, how all sweeteners must be able to replace multiple properties inherit in sugar, such as taste, nutritional content, and binding properties.About the GuestCorey Scott, PhD, is a Principal Nutrition Scientist with Cargill in Minneapolis, Minnesota, where he lea...

11 months ago

28 minutes

Adverse Reactions

Little Zombie Parasites

Co-hosts Anne Chappelle and David Faulkner speak with William J. Sullivan, PhD, Showalter Professor of Pharmacology & Toxicology and Professor of Microbiology & Immunology with the Indiana University School of Medicine, about toxic parasites lying dormant in your brain and the power and importance of science communication.About the GuestBill Sullivan, PhD, has been studying the intracellular parasite Toxoplasma gondii since he was a graduate student in the laboratory of Dr. David Roos...

12 months ago

37 minutes

Adverse Reactions

The Intersection of Toxicology, Environmental Health Law, and Justice

As the foremost experts on the effects of chemicals, biological substances, and more, toxicologists are key contributors to health regulation and laws. Law Professor and lawyer Claudia Polsky, University of California Berkeley, discusses how science can influence environmental health law, as well as environmental justice, with co-hosts Anne Chappelle and David Faulkner and reveals legal gaps in protecting public health.About the GuestClaudia Polsky, JD, MAS, is a Clinical Professor of Law and...

2 years ago

31 minutes

Adverse Reactions

Pitfalls in Pharmaceutical Production: Protecting the Actual Drug Makers

While pharmaceuticals provide positive benefits for patients, what about workers that may be exposed during production? Elizabeth M. Vancza, Merck & Co. Inc., reveals to co-hosts Anne Chappelle and David Faulkner the role of occupational toxicologists in understanding the exposure risks of pharmaceuticals, chemicals, and other substances that may affect worker health, as well as how to protect them from these exposures.About the GuestElizabeth M. Vancza, PhD, DABT, is currently an Associa...

2 years ago

23 minutes

Adverse Reactions

The Big Picture of Small Things: Nanotoxicology

Nanoparticles are manmade fibers, particulates, and other objects that are so small that when inhaled, they can escape the lungs and enter other body systems. Timothy Nurkiewicz, West Virginia University, studies the effects of these and other particulars. He discusses his inhalation and nanotoxicology research, as well as work with the National Guard on developing facemasks to protect against airborne diseases, with co-hosts Anne Chappelle and David Faulkner.About the GuestTimothy R. Nurkiew...

2 years ago

30 minutes

Adverse Reactions

Tox in the Family: Generational Exposure and DDT

Blood samples and health records for 15,000 pregnancies provides a wealth of scientific data. Add samples and records from the resultant children and grandchildren, and you have an invaluable cohort with which you can study the long-term results of events that occur during pregnancy. Barbara Cohn with the Public Health Institute is the Director of such a cohort and discusses it with co-hosts Anne Chappelle and David Faulkner, including what she and colleagues have discovered about the generat...

2 years ago

25 minutes

Adverse Reactions

Bringing Cohorts in Cahoots with Lab Science

The fields of epidemiology and toxicology sometimes find themselves at odds, but Gradient’s Julie Goodman, an epidemiologist and toxicologist, shares how the two disciplines can complement each other to evaluate public health risks. Dr. Goodman also dives into the finer points of systemic reviews and meta-analyses in her conversation with co-hosts Anne Chappelle and David Faulkner.About the GuestJulie E. Goodman, PhD, DABT, FACE, ATS, is an epidemiologist and board-certified toxicologist with...

2 years ago

31 minutes

Adverse Reactions

Estradiol Complicates Everything: Toxicology across the Gender Spectrum

When it comes to hormones, everyone has them all, but their levels are where things get interesting. How chemicals affect estrogen signaling in the brain is the research focus of Troy Roepke, Rutgers, who talks to co-hosts Anne Chappelle and David Faulkner about how gender is not easily defined biologically, what it is like to be a “fabulously queer” professor, and how science can better serve the LGBTQ+ and other marginalized communities.About the GuestTroy Roepke, PhD, is an Associate Profe...

2 years ago

28 minutes

Adverse Reactions

Up in Smoke: Where Cannabis Meets the Immune System

Since the discovery of cannabinoid receptors in the mid-1990s, researchers have been trying to determine their role and how they affect the immune system. Barbara Kaplan, Mississippi State University, discusses research in this area with co-hosts Anne Chappelle and David Faulkner and also shares what scientists are discovering about CBD, vaping, THC, and more.About the GuestBarbara Kaplan, PhD, is an Associate Professor in the Center for Environmental Health Sciences in the College of Veterin...

2 years ago

33 minutes

Adverse Reactions

Wildfire Smoke Isn’t Monkey Business

Because of natural exposure to wildfire smoke, nonhuman primates have provided an increased understanding of the long-term effects of smoke inhalation during infancy, shares Lisa Miller, University of California Davis (UC Davis). Dr. Miller also discusses with co-hosts Anne Chappelle and David Faulkner the importance of animal models in human health research and how nonhuman primates can be good models for vaccine testing, as was the case with COVID-19. About the GuestLisa A. Miller, PhD...

3 years ago

26 minutes

Adverse Reactions

Sweating It Out: Exercise versus Toxic Exposures

With nonalcoholic fatty liver disease affecting nearly a third of the US population, Luma Melo, University of Pittsburgh, describes how mouse studies have shown that low-impact exercise can help reverse liver damage. Dr. Melo also shares with co-hosts Anne Chappelle and David Faulkner how research funding works in her native Brazil and the role of Brazilian women in toxicology. About the GuestLuma Melo, PhD, University of Pittsburgh, started her scientific career in her native Brazil, ea...

3 years ago

25 minutes

Adverse Reactions

Anthropogenic Ghosts on the Coast

While no longer national news, the Deepwater Horizon oil spill is still impacting the ecological health of the Gulf of Mexico and the livelihoods of the communities that rely upon the gulf’s aquatic life, as Robert “Joe” Griffitt of the University of Southern Mississippi reveals. Dr. Griffitt and co-hosts Anne Chappelle and David Faulkner discuss how ecotoxicology is both an applied and a basic science, as well as how scientific discovery is not always a linear process. About the GuestRo...

3 years ago

26 minutes

Adverse Reactions

Lions and Vultures and Tox, Oh My

How human activity, chemical exposures, and environmental factors combine to contribute to wildlife population declines is at the forefront of the research by Dr. Caroline Moore and other teams at the San Diego Zoo Wildlife Alliance. Dr. Moore unravels the role of toxicology in wildlife conservation with co-hosts Anne Chappelle and David Faulkner. About the GuestCaroline Moore, PhD, DVM, serves the San Diego Zoo Wildlife Alliance as a Scientist in Disease Investigations. In this role, sh...

3 years ago

29 minutes