In this episode, journalist David P. Ball and outreach primary care physician Dr. Terri Aldred discuss the importance of culturally safe and trauma informed substance use care for Indigenous communities. Dr. Aldred shares how her lived experience informs her medical practice, caring for Indigenous Peoples experiencing challenges rooted in colonialism, systemic racism, and health inequities. David and Dr. Aldred also speak with Angela Thomson, Indigenous Wellness Liaison at St. Paul’s Hospital. Angela highlights how Indigenous Wellness Liaisons strengthen communication and build trust between patients and clinicians, which can promote positive health care experiences. Finally, Dr. Danièle Behn Smith, Deputy Provincial Health Officer for Indigenous Health, explores how Indigenous-specific racism is woven into our health care system and how cultural humility and accountability influence clinical practice. Dr. Behn Smith also discusses systemic barriers to care for Indigenous Peoples and the need for culturally grounded, decolonizing approaches to care.Access the show notes here (https://bit.ly/APP-S5E6).