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科研喵使用AI读文献,祝你效率百倍,访问labcat.com.cn下载。本期关注发表在《Infection》(IF:5.4)上的研究"Clinical and health economic impact of isavuconazole for treatment of invasive aspergillosis and mucormycosis: a retrospective, matched multicentre cohort study in Germany"。这项德国多中心研究比较了艾沙康唑与常规抗真菌药物治疗侵袭性曲霉病和毛霉病的临床效果与经济负担。研究纳入198名血液系统恶性肿瘤患者,发现艾沙康唑组与对照组在住院时间(44天vs.39天)和死亡率(29%vs.31%)上无显著差异,但艾沙康唑的药物成本(€22,389 vs €12,801)和总治疗成本(€49,042 vs €39,369)显著更高。研究证实艾沙康唑临床疗效与标准治疗相当,但医疗决策需考虑其较高的经济成本。